The last time Liverpool filed out in a game, they met an unforeseen defeat and that will be in their mind as they travel to the Amex Stadium to battle Brighton and Hove Albion later on Saturday.
It would be a Premier League encounter which the Reds will hope to continue their unbeaten streak as well as extend their lead on top of the league table.
However, the Reds boss Jurgen Klopp goes into the game sweating as he battles with the injury of Dejan Lovren, Joe Gomez and Joel Matip which leave him with Virgil Van Dijk as the only natural player for the central defence.
However, this could force Fabinho into falling down from the middle to pair with the former Southampton star while the depth of the middle would be covered by James Milner and Georgino Wijnaldum with Jordan Henderson probably to start from the bench with his fitness concern.
Meanwhile, Xherdan Shaqiri has been in fine form could earn him a call in the attack but at a wide position alongside Sadio Mane while Mohamed Salah and Firmino would also take their place as well.
See Probable line-up of 4-2-3-1
Alisson, Alexander-Arnold, Fabinho, Van Dijk, Robertson, Milner, Wijnaldum, Shaqiri, Firmino, Mane, Salah.