Lyon attacker Memphis Depay was amongst the goals as his side strengthened their grip on the third and final Champions League spot in the French Ligue 1 following the 2-1 win over Angers.
Lyon secured a slim victory at home to lowly Angers to move six points clear of Saint Etienne in fourth place.
Saint Etienne can close the gap back to just three points with a win at Reims later this weekend.
Dutch international star Depay scored the opening goal of the game on 14 minutes before Lyon striker Martin Terrier added a second goal for the home team with six first-half minutes left.
Lyon preserved that 2-0 lead until the final minutes of the game when midfielder Lucas Tousart put through his own net to setup a nervy finish for the Champions League chasers.
The former French champions held on for a crucial win that took their points tally to 59 points while their opponents stay in 12th position with 41 points.
Former Manchester United attacker Depay played a big part in the win over Angers.
He has been able to resurrect his ailing football career at Lyon after a disastrous spell at the Theatre of Dreams.
Memphis Depay signed for Manchester United from Dutch Eredivisie giants PSV Eindhoven in the summer of 2015 but failed to make the expected impact before joining Lyon in January 2016.